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 | Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
05/10/2022 |
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Data da última atualização: |
06/12/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
MACIAG, S. S.; BELLAVER, F. A. V.; BOMBASSARO, G. E.; HAACH, V.; MORES, M. A. Z.; BARON, L. F.; COLDEBELLA, A.; BASTOS, A. P. A. |
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Afiliação: |
SHAIANA SALETE MACIAG, Universidade Estadual do Oeste do Paraná/Guarapuava; FRANCIANA A VOLPATO BELLAVER, CNPSA; GABRIELLY E. BOMBASSARO, Instituto Federal Catarinense/Campus Concórdia; VANESSA HAACH, Universidade Federal do Rio Grande do Sul; MARCOS ANTONIO ZANELLA MORES, CNPSA; LANA FLÁVIA BARON, Universidade Federal do Rio Grande do Sul; ARLEI COLDEBELLA, CNPSA; ANA PAULA ALMEIDA BASTOS, CNPSA. |
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Título: |
On the influence of the source of porcine colostrum in the development of early immune ontogeny in piglets. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Scientific Reports, v. 12, n. 15630, 2022. |
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DOI: |
https://doi.org/10.1038/s41598-022-20082-1 |
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Idioma: |
Inglês |
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Conteúdo: |
The efects on the ontogeny of serum cytokines and immune cells caused by feeding suckling piglets with sow/gilt colostrum and milk replacer was assessed in the present study. After farrowing, the piglets born were randomized into six groups: GG and SS (n= 10/group): piglets were kept with their dam; GS (n= 10): piglets were changed from gilts to sows; SG (n= 10): piglets were changed from sows to gilts; GMR (n= 6) and SMR (n= 8): piglets from either gilts or sows were isolated from the dams and were bottle-fed ad libitum with commercial formula milk replacer. The piglets remained in the groups during the frst 24 h of life and were later returned to their respective mothers. Serum immunoglobulin concentration and lymphocyte proliferation from the blood, spleen, thymus, and mesenteric lymph node of the piglets were assessed at 24 h and at 28 days of age. Serum cytokine concentrations were measured through a cytokine multiplex assay at 24 h. Overall, piglets suckling on sows (SS and GS) had a higher concentration of serum immunoglobulin at 24 h, which was also associated with a rise in plasma cytokine concentration and greater ability of B and T cells from lymphatic organs and blood mononuclear cells to respond to mitogens. We suggest a bias towards Th1-, Th2-, and Th17-cell polarizing and cytokines during the suckling period, which may be infuenced by maternal immunological factors in the colostrum, such as dam parity. All fndings suggest sow parity having a possible role, which may contribute to exerting a modulating action on immune response development. MenosThe efects on the ontogeny of serum cytokines and immune cells caused by feeding suckling piglets with sow/gilt colostrum and milk replacer was assessed in the present study. After farrowing, the piglets born were randomized into six groups: GG and SS (n= 10/group): piglets were kept with their dam; GS (n= 10): piglets were changed from gilts to sows; SG (n= 10): piglets were changed from sows to gilts; GMR (n= 6) and SMR (n= 8): piglets from either gilts or sows were isolated from the dams and were bottle-fed ad libitum with commercial formula milk replacer. The piglets remained in the groups during the frst 24 h of life and were later returned to their respective mothers. Serum immunoglobulin concentration and lymphocyte proliferation from the blood, spleen, thymus, and mesenteric lymph node of the piglets were assessed at 24 h and at 28 days of age. Serum cytokine concentrations were measured through a cytokine multiplex assay at 24 h. Overall, piglets suckling on sows (SS and GS) had a higher concentration of serum immunoglobulin at 24 h, which was also associated with a rise in plasma cytokine concentration and greater ability of B and T cells from lymphatic organs and blood mononuclear cells to respond to mitogens. We suggest a bias towards Th1-, Th2-, and Th17-cell polarizing and cytokines during the suckling period, which may be infuenced by maternal immunological factors in the colostrum, such as dam parity. All fndings suggest sow parity having a possible role, whi... Mostrar Tudo |
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Palavras-Chave: |
Células imunes; Colostro suíno; Lactente; Ontogenia de citocinas séricas; Ontogenia imunológica. |
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Thesagro: |
Alimentação; Leitão. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02490naa a2200301 a 4500
001 2147128
005 2022-12-06
008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1038/s41598-022-20082-1$2DOI
100 1 $aMACIAG, S. S.
245 $aOn the influence of the source of porcine colostrum in the development of early immune ontogeny in piglets.$h[electronic resource]
260 $c2022
520 $aThe efects on the ontogeny of serum cytokines and immune cells caused by feeding suckling piglets with sow/gilt colostrum and milk replacer was assessed in the present study. After farrowing, the piglets born were randomized into six groups: GG and SS (n= 10/group): piglets were kept with their dam; GS (n= 10): piglets were changed from gilts to sows; SG (n= 10): piglets were changed from sows to gilts; GMR (n= 6) and SMR (n= 8): piglets from either gilts or sows were isolated from the dams and were bottle-fed ad libitum with commercial formula milk replacer. The piglets remained in the groups during the frst 24 h of life and were later returned to their respective mothers. Serum immunoglobulin concentration and lymphocyte proliferation from the blood, spleen, thymus, and mesenteric lymph node of the piglets were assessed at 24 h and at 28 days of age. Serum cytokine concentrations were measured through a cytokine multiplex assay at 24 h. Overall, piglets suckling on sows (SS and GS) had a higher concentration of serum immunoglobulin at 24 h, which was also associated with a rise in plasma cytokine concentration and greater ability of B and T cells from lymphatic organs and blood mononuclear cells to respond to mitogens. We suggest a bias towards Th1-, Th2-, and Th17-cell polarizing and cytokines during the suckling period, which may be infuenced by maternal immunological factors in the colostrum, such as dam parity. All fndings suggest sow parity having a possible role, which may contribute to exerting a modulating action on immune response development.
650 $aAlimentação
650 $aLeitão
653 $aCélulas imunes
653 $aColostro suíno
653 $aLactente
653 $aOntogenia de citocinas séricas
653 $aOntogenia imunológica
700 1 $aBELLAVER, F. A. V.
700 1 $aBOMBASSARO, G. E.
700 1 $aHAACH, V.
700 1 $aMORES, M. A. Z.
700 1 $aBARON, L. F.
700 1 $aCOLDEBELLA, A.
700 1 $aBASTOS, A. P. A.
773 $tScientific Reports$gv. 12, n. 15630, 2022.
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